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GC Biotech – CleanDTR

CleanDTR is an efficient paramagnetic bead-based system, designed to remove unincorporated dye terminators from a Sanger sequencing reaction. The CleanDTR process involves three simple steps: bind, wash and elute. By selectively binding the sequencing product to the magnetic particles, unincorporated dyes, nucleotides, salts and primers will be removed during ethanol washes. This principle allows for elution of the pure Sanger Sequencing product in the elution buffer of choice. The protocol can be adapted to your current liquid handling workstation (e.g. Beckman, Hamilton, Tecan, Caliper, Perkin Elmer, Agilent and Eppendorf), utilizing your current protocol, but it can also be used manually. For a full scope of the GC Biotech applications we suggest taking a look at our webstore.


  • Long Phred 20 read lengths averaging over 800 bps;
  • Pass rates over 85% or higher;
  • Efficient elimination of sequencing reaction contaminants;
  • Reduce BigDye usage, due to increased average signal strength.

GC biotech

GC biotech distributes products from its suppliers. As a specialist in automation for genomics, they represent the products of Bioline, CleanNA, Bionex, LGC Genomics, Denovix, Permagen, Nippon Genetics and RBC Bioscience. The emphasis lies on instruments, software, kits and reagents, developed with the aim to simplify, accelerate and improve life sciences research. GC biotech combines the representation of some of the most advanced US and EU suppliers with in-house scientific and technical know-how. Since November 2012 GC biotech is ISO 9001:2008 certified, that reflects the company’s continued commitment to the highest quality standards.

Over the years GC biotech has built a strong sales team with academic backgrounds in molecular biology. They are supported by an engineering team with years of experience in instrumentation and software. GC biotech was founded in 2003 and also manufactures CleanNA. With CleanNA, GC biotech develops and manufacturers magnetic bead- based kits with a focus on high throughput nucleic acid purification technologies for DNA sequencing applications.

Want to learn more about the CleanDTR and other GC Biotech products? Please visit the website. You can submit your contact info.